Norwegian Complement Research Group
The Norwegian Complement Research Group (NCRG), led by professor Tom Eirik Mollnes, is an informal association of scientists focusing their work mainly on the complement system, a part of the hosts’ innate immunity. The group comprises approximately 25 people located at two different laboratories in Norway, “The Bodø Laboratory” at Nordland Hospital and University of Tromsø, and “The Oslo laboratory” at Oslo University Hospital and University of Oslo.
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News
Thrombin does NOT cleave C5 under physiological conditions
A novel whole blood model revealed that thrombin does not cleave native C5. Selected by the J Immunol Editor as “Top Read”. Previous...
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NCRG goes to Blood
Plasma C5 is associated with increased risk of venous thrombosis. NCRG, here represented by Espen Waage Skjeflo (first author) and colleagues , together with TREC at the University of Tromsø, here represented by John-Bjarne Hansen (last author) and colleagues, have succeeded to show an important association between the level...
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A role for vitamin C and hydrocortison in sepsis?
First CORVOS study published. A debate is ongoing with respect to the role of vitamin C and hydrocortison in treatment of sepsis. Robust evidence is lacking in the literature since no controlled, randomized studies have been published. Thus, we went from bedside to bench and designed a human...
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The Traumatic Complement
Increased complement activation is a predictor of prognosis in trauma patients. NCRG and the Trauma Group at Ullevaal Hospital showed that TCC predicted outcome...
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